March 22, 2013

Protein folding, RMSD and Gibbs Energy

Today I was discussing with my friend Swakkhar Shatabda on the protein folding problem. Although I came to know about protein folding in one of my early courses, there is a lot more to explore.

Today, I got familiar with few metrics used to measure the distance between two conformations of protein - RMSD (Root Mean Square Deviation), cRMSD and dRMSD. One ppt file helped me understand it.  I got this file from Standord University website.

I also learned about Gibbs Free Energy.

I really enjoyed the discussion between us!

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